A lightning network wallet can be compatible with a Ledger Nano generated wallet, but doesn’t have to be.
Ledger nano generates seeds (the 24 words) using BIP 32/BIP 39/BIP 44.
I checked to see what format eclair uses, and it seems to use BIP 49 instead of BIP 44. This seems to suggest that the seeds are incompatible, but I haven’t confirmed this.
If you want to do so, you can try importing your Ledger seeds into eclair, which is a non-descructive action (i.e. it won’t affect your wallet/funds).
